UpSurgeOn, a MedTech company developing simulation technologies for surgical training, has secured €5 million in funding led by CDP Venture Capital, with participation from strategic investors.
The company is focused on improving surgical education through hybrid simulation tools that combine physical models, virtual environments, and data-driven feedback systems.
What The Company Does
Founded in 2017 by neurosurgeons Federico Nicolosi and Giannantonio Spena, UpSurgeOn develops training platforms designed to enhance psychomotor skills in surgery. Its solutions integrate augmented and virtual reality, AI, and physical simulation models to replicate real surgical conditions.
The platform enables surgeons to practice procedures in controlled, repeatable environments without relying on cadaver-based training. It also incorporates performance tracking and analytics, allowing users to measure skill development and refine techniques over time.
UpSurgeOn’s technology is used across multiple specialties, including neurosurgery, spine, plastic, ENT, and vascular surgery, and is deployed in more than 110 countries.
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Market Context / Industry Background
Surgical training is undergoing a shift toward simulation-based learning, driven by the need for safer, more scalable, and accessible education methods. Traditional training approaches, including cadaver-based practice, can be limited by cost, availability, and ethical considerations.
At the same time, healthcare systems are placing greater emphasis on patient safety and outcome consistency, increasing the importance of standardized training tools. Advances in AR, VR, and AI are enabling more realistic simulations, supporting the development of practical skills in a controlled environment.
Access to high-quality surgical training remains uneven across regions, creating demand for platforms that can deliver consistent education globally.
Founder / Investor Commentary
Federico Nicolosi, CEO and founder of UpSurgeOn, described the funding as an opportunity to expand the company’s global presence while continuing to focus on the practical needs of surgical professionals. He emphasized that the company’s work is grounded in improving patient outcomes, noting that the platform is designed to address real challenges faced in clinical environments.
Mario Scuderi, Head of the Evoluzione Fund at CDP Venture Capital, highlighted the potential impact of the company’s technology on patient safety. He pointed to the importance of improving access to high-quality training, suggesting that platforms like UpSurgeOn can help reduce disparities in surgical education across different regions.
Growth Plans / Use Of Funds
The funding will be used to support UpSurgeOn’s international expansion, as well as the development of new platform capabilities and advanced research initiatives. The company aims to further enhance its simulation technologies and broaden its application across additional medical fields.
Investment will also focus on strengthening its digital infrastructure and expanding partnerships with healthcare institutions, research organizations, and medical device companies.
About UpSurgeOn
UpSurgeOn is a MedTech company focused on surgical training through simulation technologies. Founded in 2017 and headquartered in Milan, with a presence in the United States, the company develops platforms that combine physical models, AR/VR, AI, and performance analytics. Its mission is to improve surgical education, enhance patient safety, and enable more accessible and standardized training worldwide.
